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Celebrex adult dosage: "Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine and does not interfere with the function of the blood platelets and, as a result, does not reduce clotting and lead to increased bleeding like other NSAIDs. If you are allergic to it or to sulfa drugs. Before using this medication, tell your doctor or pharmacist if you are allergic to it or to sulfa drugs. Celecoxib does not interfere with the clotting of blood. In patients with familial adenomatous polyposis. Fluconazole increases the concentration of Celecoxib in the liver."