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Very high concentrations of the drug develop within the skin, so it is effective in treating superficial fungal infections. Recent research indicates that long-term use of Nizoral helps prevent hair loss and improves the scalp condition. Nizoral stops the fungi from producing a substance called ergosterol. Very high concentrations of the drug develop within the skin, so it is effective in treating superficial fungal infections. Nizoral stops the fungi from producing a substance called ergosterol. Even after rinsing, Nizoral carries on working for several days. There are possible side-effects associated with this medicine that can affect individuals in different ways. Ketoconazole interferes with testicular secretion of testosterone and may produce a feminizing effect in males.
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