Valtrex is most effective if it is started within 48 hours of when the rash first appears. Anyone who has been diagnosed with genital herpes will need to discuss with your doctor. It can help reduce the number of outbreaks you have. Aciclovir that has greater oral bioavailability than aciclovir. Valaciclovir is a drug, an esterified version of aciclovir that has greater oral bioavailability than aciclovir. Once a day, every day.
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